The Licensing and Intellectual Property Department of JINR announces that on 11 June 2020, the Joint Institute for Nuclear Research received a patent for the invention “Method for prediction of risk of developing diseases associated with the level of immunoglobulin E(IgE) in human blood serum”. The authors of the work are Ivanova Anastasiya Evgenevna, Rusakovich Artem Nikolaevich, Kravchenko Elena Vladimirovna.

JINR staff congratulates the authors on receiving the patent for their invention!

More details about the invention

The invention refers to molecular biology and medicine. Disclosed is a method for prediction of the risk of developing diseases associated with the level of immunoglobulin E (IgE) in human blood serum. Polymorphisms rs2251746 and rs2427837 are investigated by allelic discrimination using TaqMan probes and primers. If the CT (rs2251746) allele combination with the GG allele (rs2427837) is detected, a high risk of the diseases associated with high serum IgE is predicted. When alleles are combined TT (rs2251746) and AG (rs2427837) or CT (rs2251746) and GG (rs2427837) – increased risk. When alleles are combined AG (rs2427837) and CT (rs2251746), or GG (rs2427837) and CC (rs2251746), or AA (rs2427837) and TT (rs2251746) – average risk. When alleles are combined AG (rs2427837) and CC (rs2251746) or AA (rs2427837) and CT (rs2251746) – reduced risk. When alleles are combined AA (rs2427837) and CC (rs2251746) – low risk.

EFFECT: invention provides enlarging the number of methods for prediction of development of IgEdependent diseases.