Following the holographic duality, the 4D rotating 𝒩 = 4 SYM plasma can be described by a rotating Kerr-AdS5 black hole. The Kerr-AdS5 black hole has a conformal boundary R × 𝕊3 on which the 𝒩 = 4 SYM theory (a thermal ensemble) “lives”. Moreover, the Hawking temperature corresponds to the temperature of the dual theory. We study rectangular Wilson loops in 𝒩 = 4 SYM on R × 𝕊3 at finite temperature using the holographic dictionary. Accordingly, we consider an open string in Kerr-AdS5 hanging from the conformal boundary to the horizon, so that the ends of the string correspond to “quarks”. We calculate the quark-antiquark potential from the Nambu-Goto action of the string and find that the potential includes the Coulomb and linear parts, indicating the confinement/deconfinement phase transition. We also calculate the jet-quenching parameter associated with the energy loss of a fast parton propagating through a rotating 𝒩 = 4 SYM plasma and analyse its dependence on rotation. We show that the value of the jet-quenching parameter for the rotating case can be smaller comparing to the case of the planar AdS black hole.