The Licensing and Intellectual Property Department of JINR announces that on 29 January 2021, the Joint Institute for Nuclear Research received a patent for the invention “Method for determining the presence of a genetic predisposition to longevity”. The authors of the work are Kravchenko Elena Vladimirovna and Ivanova Anastasiya Evgenevna from the Dzhelepov Laboratory of Nuclear Problems of JINR.

JINR staff congratulates the authors on receiving the patent for their invention!

More details about the invention

FIELD: biotechnology.
SUBSTANCE:invention is method for determining presence of genetic predisposition to human longevity based on data on genetic variant of rs2802288 locus. A real-time polymerase chain reaction is carried out with DNA isolated from human biological material in presence of oligonucleotide probes and primers, and rs2802288 polymorphism ofFOXO3A gene is analyzed by allelic discrimination. This is done to predict presence of genetic predisposition to human longevity, which increases by ~ 1.5 times probability of living to 100 years in case of detection of genotype AA (rs2802288) or AG (rs2802288), and absence of genetic predisposition to human longevity, which increases ~1.5 times the probability of living to 100 years in case of detection of GG genotype (rs2802288).
EFFECT: invention provides accurate, simple, fast and inexpensive method for predicting a person’s genetic disposition to longevity.